I know this is an old thread CactusFlower but I just started on Sertraline a couple of weeks ago at 50 mg, then was bumped up to 100 mg yesterday for really bad, ongoing anxiety.
I personally have had a rollercoaster of a ride with it which is apparently quite common with this medication. Everything I read from other patients is that you have to stick it out because once it kicks in and the initial symptoms abate (nausea, increased anxiety, insomnia, etc), it's excellent.
How did it go for you?